FOR LABORATORY RESEARCH PURPOSES ONLY. This compound has not received FDA approval. All information shown is drawn from published laboratory research for educational purposes
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This site sells research products exclusively to qualified researchers and laboratories for in vitro and laboratory use. Please confirm before continuing.
For research use only. Not for human consumption. Not evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. This compound has not received FDA approval. All information shown is drawn from clinical studies for educational purposes.
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Lab-verified quality
Each lot is analysed by Bioviridian before release. Below is the Certificate of Analysis for the most recent lot, as issued by the laboratory.
Overall purity
99.8%
RP-HPLC (214 nm)
View the signed COA (PDF)Check this certificate at bioviridians.com/coa-search.html with code COA7694.
Test results
5 of 5 conformHPLC retention time 10.011 min · Signed: Shane Straight, M.S., Principal Chemist, Bioviridian Inc.
Every lot keeps its own signed certificate. Lots are listed newest first.
Lot MOTC072026-MG
99.8%
Overall purity
Tested July 13, 2026
Open COAEarlier lots will appear here as new Certificates of Analysis are published.
Compound details
Molecular profile
Storage requirements
Store lyophilized MOTS-c at −20°C for long-term stability.
Once reconstituted, refrigerate at 2–8°C and use within 4–6 weeks.
Published literature
3 peer-reviewed publications indexed on PubMed. Listed for reference only; inclusion does not imply any use, effect or endorsement.
CELL METAB · 2018
Kim KH, Son JM, Benayoun BA, et al. Cell Metab. 2018;28(3):516-524.e7. doi:10.1016/j.cmet.2018.06.008
Examined the translocation of MOTS-c to the nucleus under metabolic stress in cultured cells and its interaction with NRF2/ARE-regulated gene expression.
NAT COMMUN · 2021
Reynolds JC, Lai RW, Woodhead JST, et al. Nat Commun. 2021;12(1):470. doi:10.1038/s41467-020-20790-0
Measured endogenous MOTS-c levels in response to exercise and studied its administration in young, middle-aged and old mice with assessment of skeletal-muscle gene expression and physical performance measures.
BIOESSAYS · 2019
MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus
Benayoun BA, Lee C. Bioessays. 2019;41(9):e1900046. doi:10.1002/bies.201900046
Reviewed the discovery of MOTS-c and the evidence for mitochondrial-to-nuclear signaling by this mitochondrial-derived peptide.
