TB-500 (Thymosin Beta-4) – 10mg

TB-500, also known as Thymosin Beta 4 or TB-4, is a synthetic version of a peptide found naturally in human cells, supplied here in a 10mg quantity for laboratory research use only. This 43-amino-acid peptide has high solubility in water and a lightweight structure. Research has explored its relationship with actin, the protein responsible for cell structure, movement, and division, particularly in studies of cellular migration and structural signaling. This compound is intended for research use only, and its applications outside of laboratory settings have not been established.

TB-500 is a synthetic peptide fragment of Thymosin Beta-4, supplied by Peppy Peptides exclusively for laboratory research use. Each batch is manufactured to 99% purity and independently third-party tested, providing researchers with a consistent, well-characterized fragment for controlled cellular-signaling research.

What is TB-500 (Thymosin Beta-4)?

TB-500 is a synthetic peptide fragment derived from Thymosin Beta-4, a naturally occurring 43-amino-acid protein present in most human and animal cells. TB-500 corresponds to the active-site region of the full-length protein and belongs to the broader class of actin-binding peptides. Because of this structural relationship, TB-500 is studied in laboratory research for its interaction with cellular-migration and tissue-repair signaling pathways, including its documented binding to actin, a structural protein involved in cell movement and cytoskeletal organization. Researchers use TB-500 as a reference fragment when studying the signaling behavior of the full-length Thymosin Beta-4 protein in cell-based and animal-model systems. Peppy Peptides supplies TB-500 strictly as a research compound, intended for qualified laboratory personnel in controlled research settings.

Research Applications

TB-500 is commonly referenced in laboratory literature examining cellular-migration signaling, where researchers study its interaction with actin-binding pathways in cell-based models. It is also examined in research contexts related to tissue-repair signaling, including in vitro models of wound-margin cell migration and angiogenesis-related pathways. Some published research has explored TB-500’s interaction with cytoskeletal-organization pathways relevant to cell shape and motility studies. Researchers investigating the structure-activity relationship between peptide fragments and their parent proteins have used TB-500 as a reference compound when comparing fragment activity to full-length Thymosin Beta-4 in laboratory assays. As with all compounds supplied by Peppy Peptides, TB-500 is intended solely for in vitro and animal-model laboratory research, never for use in humans or animals outside of a licensed research setting.

Purity & Third-Party Testing

Every batch of Peppy Peptides TB-500 is manufactured to a minimum of 99% purity. Purity and identity are verified through independent third-party testing using high-performance liquid chromatography (HPLC) and mass spectrometry. A Certificate of Analysis (COA) documenting these results is available for every batch at peppyshop.com/certificate-of-analysis/, allowing researchers to confirm compound identity before use. Each COA lists the specific analytical methods and reference standards applied, giving researchers documentation they can cite directly in laboratory protocols and publications.

Storage & Handling

TB-500 is supplied in lyophilized (freeze-dried) form and should be stored at −20°C for long-term stability. Once reconstituted, store the solution refrigerated at 2–8°C and use within 4–6 weeks. Avoid repeated freeze-thaw cycles to preserve compound integrity throughout the research period.

Frequently Asked Questions

What purity is Peppy Peptides TB-500 (Thymosin Beta-4)?

Peppy Peptides TB-500 (Thymosin Beta-4) is supplied at 99% purity, verified by independent third-party HPLC testing and mass spectrometry. A Certificate of Analysis is available for every batch.

How should TB-500 (Thymosin Beta-4) be stored?

Store lyophilized TB-500 at −20°C for long-term stability. After reconstitution, refrigerate at 2–8°C and use within 4–6 weeks.

What is TB-500 studied for in laboratory research?

TB-500 is studied in laboratory research for its interaction with cellular-migration and tissue-repair signaling pathways.

Published laboratory research on Thymosin Beta-4 is indexed on PubMed.

For research use only. Not for human consumption. Not evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease.